Prof. Ruedi Aebersold

Ruedi Aebersold

Prof. Ruedi Aebersold was born 1954 and is a Swiss-Canadian.
He studied in Basel/Switzerland and made his Ph.D. in Cellular Biology at the Biocenter of the University Basel in 1983.
He was Post-Doc at the California Institute of Technology, Pasadena.
From 1989 to 1993 Ruedi Aebersold was Assistant Professor at the Department of Biochemistry, University of British Columbia.
Starting in 1993, he was Associate Professor, then Professor at the Department of Molecular Biotechnology, University of Washington, Seattle.

In 2000 he co-founded the Institute of Systems Biology in Seattle. This Institute is a non-profit research institute dedicated to predicting and preventing diseases. It rapidly grew to a faculty of eight and a staff of more than 170. "The Institute is already one of this country's most influential biotech facilities ..." stated United States Senator Patty Murray. "The Institute has introduced a new way of doing science, and it's going to have global impact."

Ruedi Aebersold is a world leader in analytical protein biochemistry and proteomics. He leads a research group at the Institute of Systems Biology, that is focused on developing new methods and technologies for understanding the structure, function and control of complex biological systems.
The completion of the genomic sequence of a number of species has catalyzed new research approaches to study the structure, function and control of biological processes. These include the abundance, specific activity, state of modification and structure of proteins as well as their ability to interact with other biomolecules. They are characterised by the systematic and in many cases quantitative analysis of all the molecules of a particular type expressed by a cell or tissue. Ruedi Aebersold's laboratory is focussing on the development and the application of proteomics tools, i.e. tools to systematically study the proteins expressed by a cell or tissue. He has developed a generic quantitative approach that combines the use of chemical reagents for the selective isolation of specific classes of peptides, stable isotope incorporation for accurate quantification, and tandem mass spectrometry for the identification of the selected peptides.

During his scientific career so far he issued more than 250 peer reviewed publications. He is member of several editorial boards in the field of protein science, genomics and proteomics. He is also teaching as Professor at the University of Zürich in Switzerland.